I always wondered why Peter was strict keto for 3 years and then stopped abruptly. I suspect the family hx and early CVD had something to do with it. Maybe the increased sat fat intake was driving up his ApoB ?
Whatās the next trend youāll be 5-10 years ahead of Robb??
This book was FANTASTIC!!!! Hands down one of my favoritesā¦
And now I want to pick your brain on several things ā one being metformin. The entire time I was reading I couldnāt help but wonder if you are checking off all the boxes ā zone 2 strength sleep decent diet - if youāre fostering healthy relationships - I mean if youāre doing a decent job at taking care of yourself but you still see glucose creeping up and have a few autoimmune issuesā would metformin be worth a shot????
Last check A1C was 5.3. Fasting makes me pauses several days a weekā¦ over 100 on occasions. I can keep it down if Iām in a sizable CR state - but who wants live perpetually under fueled? For record - Iām pretty lean. Not sure that matters āalso I runā I worry that metformin will lower my lactate threshold for running thus making it impossible to improve - is that a stupid worry? I just feel like you donāt hear much about how some of the longevity drugs affect exercise?
Meanwhile ā Iāve been SHOCKED at how available prescription for metformin is online (under the pretense of weight loss) ā is this a good or bad thing?? Andā¦ the rest of the entire country seems to be eating their twinkies with a dose of once weekly mounjaro and preaching to the commoners about climate change from their private jetā¦. I feel like we live in the upside down.
i've been following your work since i read Paleo Solution in 2011/2012. great read. i'm new to your fasting critique. are you against daily or 2-3 times a week 16:8 or even 12:12? or are you just saying 20-24hrs daily is too much?
If it's working for a person, great, but I've just seen a lot of folks cook themselves. They were fasting when (IMO) they should have been lifting weights.
Thanks for the review! I pre-ordered the book same day I got the announcement, so I've been waiting eagerly to get it in my hands! Glad to hear that you really enjoyed it!
Great article Robb, and let's make no bones about it, you reached these conclusions a little bit before Peter did! I watched your 'Longevity: are we trying too hard" a few days ago and am just about to re-watch it. I believe you picked up on a truly groundbreaking concept: functional muscle mass is the key correlate to long healthspan. (interestingly Dr Lyon has arrived upon this same key message, albeit from a different perspective). So that fires up a very different question in my mind - if this is true then do we not want to be dosing high-quality protein throughout all our waking hours (say every 3-4 hours)? Currently I do a nice gentle 16:8 fast most days which gives me some very pleasant mental clarity in the mornings before breaking my fast at 12pm. No cravings or anything later in the day, so all very comfortable. But surely the implications of what you and Peter are saying is that it would be better to have say a 30g pure whey protein isolate shake upon waking, and another just before bed to leverage the exercise (resistance or cardio) performed during the day? ie the optimum scenario to promote lean muscle mass (and therefore longevity) might be a very short 8-hour fasting window? This has blown my mind a bit - please could you let us know your views? Maybe even worthy of a separate article for you to address this?
Great read, Robb. Peter is a brilliant person and itās been interesting following him over the past several years and seeing his viewpoints change with both new evidence combined with his own self experimentation. Iām pleased that people like Peter (and you) are preaching the value of building your body to be resilient (quality protein intake, well-rounded fitness program, sleep, etc) as opposed to the overly ārestrictiveā and/or gimmicky model (too much fasting, too little protein, biohacking like a crazy person, etc)āit feels that the pendulum is starting to swing to the ābuild a resilient bodyā model in many camps and from many health experts. This change in approach has been paramount for my own personal health journey. As Mark Sisson has been known to say, āLive Long. Drop Deadā.
Thanks for writing this review. I am an avid TheDrive podcast fan (Dr.Attiaās weekly podcast which has covered most of this material in more depth with his expert guests.) I could listen to Peter all day - like chatting with a very interesting very knowledgeable very accomplished very fun (my idea of fun anyway!) guy. I canāt imagine that he wouldnāt be my first choice to drag along on a challenging hike or to an important discussion of a life or death decision (like how to outlive.) The man knows how to tackle an issue! So so many āexpertsā are so limited in depth and breadth. Dr Attia is a breath of fresh air. ā¤ļø thx again for your detailed review.
"There is a pasty, sarcopenic huckster in the health space claiming he is going to make it to 150 years old"
Oooooooof shots fired! ššššš
Who is he referring to ??
Robb I always love your take on most things. I really wish you would write more!
Thank you!! I'll be back at it more. It's been very busy between work, homeschooling the kids etc, but I'll carve out more time.
The nickname for Peter Attia in our house is "The Winner." He just is.
Thanks Robb!
I always wondered why Peter was strict keto for 3 years and then stopped abruptly. I suspect the family hx and early CVD had something to do with it. Maybe the increased sat fat intake was driving up his ApoB ?
Whatās the next trend youāll be 5-10 years ahead of Robb??
Stay salty !
Too kind! Interestingly, I think Peter can eat sat'd fat with absolute abandon and it does not alter ApoB at all.
Itās a bit more complicated than that. Listen to this clip, and ideally the whole podcast which is excellent: https://podclips.com/c/saturated-fat-consumption-increases-ldl-cholesterol
Robb, stitcher is going away soon. Where will your podcast reside? . I do not do apple.
We are on all major podcast platforms! Libsyn is a good option: https://thehealthyrebellionradio.libsyn.com/
Thanks, Robb.
This book was FANTASTIC!!!! Hands down one of my favoritesā¦
And now I want to pick your brain on several things ā one being metformin. The entire time I was reading I couldnāt help but wonder if you are checking off all the boxes ā zone 2 strength sleep decent diet - if youāre fostering healthy relationships - I mean if youāre doing a decent job at taking care of yourself but you still see glucose creeping up and have a few autoimmune issuesā would metformin be worth a shot????
Could be worth a shot for sure. Is A1C going up (so total increase) or just fasting AM?
Last check A1C was 5.3. Fasting makes me pauses several days a weekā¦ over 100 on occasions. I can keep it down if Iām in a sizable CR state - but who wants live perpetually under fueled? For record - Iām pretty lean. Not sure that matters āalso I runā I worry that metformin will lower my lactate threshold for running thus making it impossible to improve - is that a stupid worry? I just feel like you donāt hear much about how some of the longevity drugs affect exercise?
Meanwhile ā Iāve been SHOCKED at how available prescription for metformin is online (under the pretense of weight loss) ā is this a good or bad thing?? Andā¦ the rest of the entire country seems to be eating their twinkies with a dose of once weekly mounjaro and preaching to the commoners about climate change from their private jetā¦. I feel like we live in the upside down.
Alas.
i've been following your work since i read Paleo Solution in 2011/2012. great read. i'm new to your fasting critique. are you against daily or 2-3 times a week 16:8 or even 12:12? or are you just saying 20-24hrs daily is too much?
If it's working for a person, great, but I've just seen a lot of folks cook themselves. They were fasting when (IMO) they should have been lifting weights.
Great Robb that was such a good read, thank you for the review.
Thanks for the review! I pre-ordered the book same day I got the announcement, so I've been waiting eagerly to get it in my hands! Glad to hear that you really enjoyed it!
Awesome review, Robb. I had already bought the book and plan on also gifting it to my 80 year old dad and 52 year old brother.
This is an excellent review- I preordered this book and look forward to reading it!
Iām really looking forward to this book!
Great article Robb, and let's make no bones about it, you reached these conclusions a little bit before Peter did! I watched your 'Longevity: are we trying too hard" a few days ago and am just about to re-watch it. I believe you picked up on a truly groundbreaking concept: functional muscle mass is the key correlate to long healthspan. (interestingly Dr Lyon has arrived upon this same key message, albeit from a different perspective). So that fires up a very different question in my mind - if this is true then do we not want to be dosing high-quality protein throughout all our waking hours (say every 3-4 hours)? Currently I do a nice gentle 16:8 fast most days which gives me some very pleasant mental clarity in the mornings before breaking my fast at 12pm. No cravings or anything later in the day, so all very comfortable. But surely the implications of what you and Peter are saying is that it would be better to have say a 30g pure whey protein isolate shake upon waking, and another just before bed to leverage the exercise (resistance or cardio) performed during the day? ie the optimum scenario to promote lean muscle mass (and therefore longevity) might be a very short 8-hour fasting window? This has blown my mind a bit - please could you let us know your views? Maybe even worthy of a separate article for you to address this?
Great read, Robb. Peter is a brilliant person and itās been interesting following him over the past several years and seeing his viewpoints change with both new evidence combined with his own self experimentation. Iām pleased that people like Peter (and you) are preaching the value of building your body to be resilient (quality protein intake, well-rounded fitness program, sleep, etc) as opposed to the overly ārestrictiveā and/or gimmicky model (too much fasting, too little protein, biohacking like a crazy person, etc)āit feels that the pendulum is starting to swing to the ābuild a resilient bodyā model in many camps and from many health experts. This change in approach has been paramount for my own personal health journey. As Mark Sisson has been known to say, āLive Long. Drop Deadā.
This is great thank you
Thanks for writing this review. I am an avid TheDrive podcast fan (Dr.Attiaās weekly podcast which has covered most of this material in more depth with his expert guests.) I could listen to Peter all day - like chatting with a very interesting very knowledgeable very accomplished very fun (my idea of fun anyway!) guy. I canāt imagine that he wouldnāt be my first choice to drag along on a challenging hike or to an important discussion of a life or death decision (like how to outlive.) The man knows how to tackle an issue! So so many āexpertsā are so limited in depth and breadth. Dr Attia is a breath of fresh air. ā¤ļø thx again for your detailed review.